Keynote Lecture Donnerstag

Die Keynote Lectures zählen zu den besonderen Highlights des Programms. In halbstündigen Vorträgen stellen herausragende Experten wichtige Themen in umfassender Weise dar.

Donnerstag, 29.9.2016, 11:30 – 12:00
von Graefe Saal
Keynote Lecture:
The sun and the eye
(engl.)

Moderator:
Horst Helbig (Regensburg)

Keynote Speaker:
Minas Coroneo

Sydney, AUS

Obwohl Sehen nur bei Licht möglich ist, kann Licht aus dem sichtbaren Wellenspektrum das Auge genauso schädigen wie UV-oder Infrarotstrahlung. Professor Minas Coroneo beschäftigt sich seit vielen Jahren mit der Pathophysiologie des Augenepithels und den Auswirkungen von Sonnenlicht auf das Auge. In der ersten Keynote Lecture des Kongresses präsentiert er seine neuesten Erkenntnisse.

Professor Minas Coroneo ist Direktor des Departments für Ophthalmologie an der University of New South Wales in Sydney. Seine translationalen Forschungsprojekte führten zur Entwicklung von Glaukom Stents (CyPass) und Intraokularlinsen der nächsten Generation sowie des okularen Farbstoffs Trypanblau (VisionBlue ®). Coroneo war in nationalen und internationalen Beratungsgremien tätig und fungierte als internationaler Berater der American Academy of Ophthalmology.

While dependent on visible light, the eye can be damaged by these and the contiguous ultraviolet (UV) and infrared wavelengths. The ophthalmohelioses pose a significant problem to the eye health of many communities and have a large impact on patients’ quality of life. Evidence that peripheral light focusing by the anterior eye to the sites of usual locations of pterygium and cortical cataract plays a role in the pathogenesis of these conditions will be reviewed. Recognition of the light pathways involved with foci at stem cell niches has directed our investigations into inflammatory and matrix metalloproteinase-related pathophysiologic mechanisms. An understanding of the molecular mechanisms involved has provided some insight into how medical treatments have been developed for the effective management of ocular surface squamous neoplasia. Peripheral light focusing has also provided direction in disease prevention with improved sunglass design and the further development of UV-blocking contact lenses. We developed UV fluorescence photography to demonstrate preclinical ocular surface solar damage and as an objective biomarker of ocular sun exposure – an inverse relationship with myopia has been demonstrated. The conundrum of the public health message about solar exposure and vitamin D deficiency will be reviewed. While the role of UV light in retinal pathology is less certain, evidence for its involvement will be discussed. The eye may play a role in the development of individualized assessment techniques of solar damage, perhaps allowing us to provide better advice to both individuals and populations.